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    Breast Cancer

    CancerTools.org: The home for cancer research tools

    Breast cancer has become a leading cause of cancer deaths among female cancer patients due to its high incidence. Consequently, it generates a considerable amount of research interest from scientists globally. 

    At CancerTools.org, we have curated an extensive collection of cell lines, antibodies and associated reagents, and made them available to scientists in pursuit of their groundbreaking breast cancer research towards understanding cancer cell biology, tumour-immunology, disease mechanisms, cancer genomics, drug design and discovery. 

    The collection is supporting cancer scientists to uncover new cancer pathways, develop in vitro cancer models and gain a better understanding of cancer. 

     

    Cell lines Organoids Plasmax Experimental models Antibodies

    Cell lines

    This collection features cell lines with key functions and high relevance in breast cancer research, including: 

     

    Anti-oestrogen resistant breast cancer cell lines Cell lines with recurrent chromosomal aneuploidies Immortalised human breast epithelial cell lines
    Derived from human breast cancer cell lines MCF-7 and T47D which depend on oestrogen for growth and demonstrate resistance to hormone-dependent breast cancer treatments, the anti-oestrogen resistant cell lines offer the potential for developing novel predictive biomarkers for therapy response and an improved understanding of the underlying molecular mechanisms of resistance, supporting new drug discovery. Derived from mouse mammary glands, NCI-HPN-F cell lines demonstrate recurrent chromosomal aneuploidies enabling investigation and identification of tumourigenesis-related cancer-specific genes and signalling pathways.  Immortalised using SV40, human breast epithelial 
    cell lines are models to study differentiation and 
    phenotypic transformation. 

    Anti-oestrogen resistant breast cancer cell lines

    Cell lines with recurrent chromosomal aneuploidies

    https://www.cancertools.org/cell-lines/161023
    NCI-HPN-F1A Mam
    Cat. #161023
    https://www.cancertools.org/cell-lines/161041
    NCI-HPN-F1G-Mam
    Cat. #161041
    www.cancertools.orghubfsCell lines 460 x230-8-1
    NCI-HPN-F1I Mam
    Cat. #161050
    www.cancertools.orghubfsCell lines 460 x230-8-1
    NCI-HPN-F23-Mam
    Cat. #161064
    www.cancertools.orghubfsCell lines 460 x230-8-1
    NCI-HPN-F24-Mam
    Cat. #161065
    www.cancertools.orghubfsCell lines 460 x230-8-1
    NCI-HPN-F43-Mam
    Cat. #161066
    www.cancertools.orghubfsCell lines 460 x230-8-1
    NCI-HPN-F44-Mam
    Cat. #161067

    Immortalised human breast epithelial cell lines 

    www.cancertools.orghubfsCell lines 460 x230-8-1
    fR5 cell line
    Cat. #153247
    www.cancertools.orghubfsCell lines 460 x230-8-1
    fR2 cell line
    Cat. #153246
    www.cancertools.orghubfsCell lines 460 x230-8-1
    SVCT cell line
    Cat. #152701
    www.cancertools.orghubfsCell lines 460 x230-8-1
    SVCT-MI2 cell line
    Cat. #152596
    www.cancertools.orghubfsCell lines 460 x230-8-1
    1-7 CE1 cell line
    Cat. #151503

    Organoids

    160957 - 765 x 500-1
    RMAM007-3 Breast cancer organoid
    Cat. #160957

    PlasmaxTM

    156371 - 765 x 500
    Plasmax cell culture medium
    Cat. #156371

    Experimental models

    Experimental models 460x230-8
    MMTV TET-LRH-1 Transgenic Mouse
    Cat. #153997
    Experimental models 460x230-8
    MUC1 Mouse
    Cat. #151555

    Antibodies

    This collection features antibodies for targets with key functions and high relevance in breast cancer research, including:

    Tumour suppressors Oncogenes Tumour associated antigens Other
    Tumour suppressors with key roles in biological processes across different types of 
    tumours as well as those altered in a specific set of cancer types, such as breast, ovarian and pancreatic cancers.    		 Oncogenes, such as c-MYC, a molecule of high interest in breast cancer research due to its regulation of key biological processes in the tumour microenvironment, e.g. angiogenesis, tumour evasion, invasion, and migration. Tumour associated antigens, e.g., MUC1 which is aberrantly overexpressed in 90% of human breast cancer, thus representing a promising marker for breast cancer diagnosis and prognosis. 

    Tumour suppressors

    Antibodies 460 x230-8
    Anti-p53 [DO-11]
    Cat. #153402
    Antibodies 460 x230-8
    Anti-p53 [DO-12]
    Cat. #153403
    Antibodies 460 x230-8
    Anti-p53 [Pab DO-1]
    Cat. #151147
    Antibodies 460 x230-8
    Anti-p53 [Pab 240]
    Cat. #151146
    Antibodies 460 x230-8
    Anti-p53 [Pab 246]
    Cat. #151412
    Antibodies 460 x230-8
    Anti-Rb1 [Rb1 (1F8)]
    Cat. #151156
    Antibodies 460 x230-8
    Anti-Phospho-Rb (Ser608) [51B7]
    Cat. #153409
    Antibodies 460 x230-8
    Anti-Phospho-Rb (Thr356) [7F10]
    Cat. #153190
    Antibodies 460 x230-8
    Anti-PALB2 [M41-P3F3
    Cat. #152698
    Antibodies 460 x230-8
    Anti-pS114-BRCA1 [3C10G8]
    Cat. #156496
    Antibodies 460 x230-8
    Anti-BRCA2 [MTA42]
    Cat. #151571
    Antibodies 460 x230-8
    Anti-Maspin [16F7]
    Cat. #161584

    Oncogenes

    Antibodies 460 x230-8
    Anti-cMyc [9E10]
    Cat. #151067
    Antibodies 460 x230-8
    Anti-cMyc [9E11]
    Cat. #151068
    Antibodies 460 x230-8
    Anti-Omomyc [21-1-3]
    Cat. #153657
    Antibodies 460 x230-8
    Anti-BCL1 [bcl-2/124]
    Cat. #151407

    Tumour associated antigens

    Antibodies 460 x230-8
    Anti-MUC1 [SM3]
    Cat. #151161
    Antibodies 460 x230-8
    Anti-MUC1 [HMFG1]
    Cat. #151495

    Other

    Antibodies 460 x230-8
    Anti-Cytochrome P450 1B1 [5D3]
    Cat. #153656
    Antibodies 460 x230-8
    Anti-SNAIL1 [20C8]
    Cat. #151548
    Antibodies 460 x230-8
    Anti-NKG2D monoclonal antibody [1D11]
    Cat. #161644
    Antibodies 460 x230-8
    Anti-NKG2D monoclonal antibody [5c6]
    Cat. #161645
    Antibodies 460 x230-8
    Anti-HLA-G [o1G]
    Cat. #161665
    Antibodies 460 x230-8
    Anti-HLA-G [87G]
    Cat. #161666

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