ANTIBODIES
Contributor Information
- Name Jack A Schalken
- Institute Radboud University Medical Center (UMC)
Tool Details
- Tool name: Anti-Cadherin 11 [16a]
- Alternate names: CDH11, Cadherin 11, Cadherin-11
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Application: WB
- Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherins are known to be involved in cell migration. Changes in cadherin expression can be involved in the metastasis of cancerous cells impacting the stage, grade and prognosis of carcinomas.
- Immunogen: Glutathione-S-transferase (GST) fusion protein of the extracellular domain of cadherin-11
- Research area: Cell biology; Cancer
- Myeloma used: Sp2/0
- For Research Use Only
Target Details
- Target: Extracellular domain of cadherin-11
- Target background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherins are known to be involved in cell migration. Changes in cadherin expression can be involved in the metastasis of cancerous cells impacting the stage, grade and prognosis of carcinomas.
Application Details
- Application: WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Tomita et al. 2000. Cancer Res. 60(13):3650-4. PMID: 10910081.
- • Bussemakers et al. 2000. Int J Cancer. 85(3):446-50. PMID: 10652439.
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