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Contributor Information

  • Name Carl Blobel
  • Institute Hospital for Special Surgery

Tool Details

  • Tool name: Anti-ADAM15 [15MODIS]
  • Clone: 15MODIS
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rabbit
  • Molecular weight of the target: ~100 kDa
  • Application: WB
  • Description: ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules.
  • Immunogen: Disintegrin domain, cysteine-rich region and an epidermal growth factor repeat from murine ADAM15
  • Research area: Cell biology; Cancer; Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: ADAM15
  • Target molecular weight: ~100 kDa
  • Target background: ADAM15 is an active metalloproteinase with gelatinolytic and collagenolytic activity which plays a role in the wound healing process. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules.

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: Whole serum
  • Storage conditions: -20°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Horiuchi et al. 2003. Mol Cell Biol. 23(16):5614-24. PMID: 12897135.
  • •  Krätzschmar et al. 1996. J Biol Chem. 271(9):4593-6. PMID: 8617717.
  • •  Lum et al. 1998. J Biol Chem. 273(40):26236-47. PMID: 9748307.
  • •  Maretzky et al. 2009. Biochem J. 420(1):105-13. PMID: 19207106.
  • •  Maretzky et al. 2009. Cancer Res. 69(11):4573-6. PMID: 19487280.