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Contributor Information

  • Name Arnoud Sonnenberg
  • Institute Netherlands Cancer Institute

Tool Details

  • Tool name: Anti-CD104 (Integrin Beta4) [58XB4]
  • Alternate names: ITGB4; GP15
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 202 kDa
  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB
  • Description: The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia.
  • Immunogen: The full length CD104 protein
  • Isotype: IgG2a
  • Research area: Cell biology; Cancer; Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: CD104
  • Target molecular weight: 202 kDa
  • Target background: The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia.

Application Details

  • Application: ELISA ; FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Geerts et al. 1999. J Cell Biol. 147(2):417-34. PMID: 10525545.