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Contributor Information

  • Institute University of Florida

Tool Details

  • Tool name: Anti-protein argonaute-2 [4F9-5C5]
  • Alternate names: AGO2; EIF2C2
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Rat ; Mouse
  • Host: Mouse
  • Application: WB ; IF ; IP
  • Description: Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs.
  • Immunogen: Pristane-primed and recombinant full length human protein
  • Isotype: IgA kappa
  • Research area: Genetics

  • For Research Use Only

Target Details

  • Target: Protein argonaute-2
  • Target background: Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs.

Application Details

  • Application: WB ; IF ; IP

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Ikeda et al. 2006. J Immunol Methods. 317(1-2):38-44. PMID: 17054975.