ANTIBODIES

Contributor Information
- Institute University of Florida
Tool Details
- Tool name: Anti-protein argonaute-2 [4F9-5C5]
- Alternate names: AGO2; EIF2C2
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human ; Rat ; Mouse
- Host: Mouse
- Application: WB ; IF ; IP
- Description: Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs.
- Immunogen: Pristane-primed and recombinant full length human protein
- Isotype: IgA kappa
- Research area: Genetics
- For Research Use Only
Target Details
- Target: Protein argonaute-2
- Target background: Protein argonaute-2 plays a role in RNA interference and contains a PAZ and PIWI domain. Ago2, in humans, is responsible for the endonuclease cleavage of targeted mRNA and interacts with GW182 (mRNA binding protein) which is a marker for cytiplasmic foci called GW bodies. This monoclonal antibody may be useful in detecting functional microRNAs.
Application Details
- Application: WB ; IF ; IP
Handling
- Format: Liquid
- Storage buffer:
- Storage conditions:
- Shipping conditions: Shipping at 4ðC
References
- • Ikeda et al. 2006. J Immunol Methods. 317(1-2):38-44. PMID: 17054975.