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Contributor Information

  • Name Ayham Alnabulsi
  • Institute Vertebrate Antibodies Limited

Tool Details

  • Tool name: Anti-UCP1 [Vab12 P4B12*A12]
  • Clone: Vab12 P4B12*A12
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
  • Immunogen: Ovalbumin-conjugated synthetic peptide - (10 amino acids) derived from the middle polypeptide region of human UCP1. The exact sequence is proprietary.
  • Isotype: IgG1 kappa
  • Research area: Cancer; Cell signaling and signal transduction; Metabolism
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1)
  • Target background: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Application Details

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.
  • •  The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer.