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Contributor Information

  • Name Karen Pulford
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-Cytokeratin [K92]
  • Clone: K92
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 55-56 kDa
  • Application: IHC ; WB
  • Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles.
  • Immunogen: Hair keratin
  • Isotype: IgG1
  • Research area: Cancer; Cell biology; Cell signaling and signal transduction
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Cytokeratins of 55 and 56 kDa
  • Target molecular weight: 55-56 kDa
  • Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles.

Application Details

  • Application: IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Pulford et al. 1985. Histopathology. 9(8):825-40. PMID: 2414204.
  • •  Gatter et al. 1985. Histopathology. 9(8):805-23. PMID: 2414203.
  • •  The characterization of two monoclonal anti-keratin antibodies and their use in the study of epithelial disorders.
  • •  Human lung tumours: a correlation of antigenic profile with histological type.