ANTIBODIES

CancerTools.org: The home for cancer research tools

Back

Anti-ADAM19 [19MOCYT]

Cat. #152534

Tool name: Anti-ADAM19 [19MOCYT]
Clone: 19MOCYT
Tool type: Antibodies
Tool sub-type: Primary antibody
Class: Polyclonal
Conjugate: Unconjugated
Reactivity: Mouse
Host: Rabbit
Molecular weight of the target: ~120 kDa
Application: WB
Description: ADAM19, is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. Later works describe ADAM19 in the bone, muscle, lung, heart, brain, kidney, and a wide range of tissues. Also reported is a sequence of ADAM19 lacking the transmembrane and cytoplasmic domains, suggesting that a soluble form is produced. Other ADAMs family members (ADAM-10, ADAM-17) have been more thoroughly studied, and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions.
Immunogen: GST-fusion protein with the cytoplasmic domain of murine ADAM19
Research area: Cancer; Cell signaling and signal transduction

Target: ADAM19
Target molecular weight: ~120 kDa
Target background: ADAM19, is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. Later works describe ADAM19 in the bone, muscle, lung, heart, brain, kidney, and a wide range of tissues. Also reported is a sequence of ADAM19 lacking the transmembrane and cytoplasmic domains, suggesting that a soluble form is produced. Other ADAMs family members (ADAM-10, ADAM-17) have been more thoroughly studied, and are known to play key roles in inflammation, growth factor maturation and release, and a wide range of other functions.

£ 300
This fee is applicable only for non-profit organizations

Quantity:

For any enquiries, please, contact us .