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Contributor Information

  • Name Fiona Watt
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Envoplakin [CRENV-1]
  • Clone: CRENV-1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: Envoplakin is a component of the cornified envelope (epidermal barrier) and a member of the plakin family of cytoskeletal linker proteins. It has been shown to be a precursor of the cornified envelope and has homology to desmoplakin amongst other keratin binding proteins.
  • Isotype: IgG1
  • Research area: Cell biology; Cell signaling and signal transduction
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Envoplakin
  • Target background: Envoplakin is a component of the cornified envelope (epidermal barrier) and a member of the plakin family of cytoskeletal linker proteins. It has been shown to be a precursor of the cornified envelope and has homology to desmoplakin amongst other keratin binding proteins.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Poot et al. 2013. Br J Dermatol. 169(5):1016-24. PMID: 23796242.
  •   Laboratory diagnosis of paraneoplastic pemphigus.