ANTIBODIES

Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-TAL1 [2TL75]
- Clone: 2TL75
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP
- Description: TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.
- Immunogen: Recombinant protein
- Isotype: IgG1 kappa
- Research area: Cancer; Cell biology; Developmental biology; Genetics; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: TAL1
- Target background: TAL-1 is a member of the helix-loop-helix family of transcription factors. Overexpression of the TAL-1 gene is the most common molecular abnormality found in human T cell leukaemia.
Application Details
- Application: IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Delabesse et al. 1998. Br J Haematol. 102(2):449-57. PMID: 9695959.
- • TAL1 expression does not occur in the majority of T-ALL blasts.
- • Bernard et al. 1995. Blood. 85(11):3356-7. PMID: 7756670.
- • Nuclear localization of the SCL/TAL1 basic helix-loop-helix protein is not dependent on the presence of the basic domain.
- • Pulford et al. 1995. Blood. 85(3):675-84. PMID: 7833471.
- • Expression of TAL-1 proteins in human tissues.