EXPERIMENTAL MODELS

Contributor Information
- Name Bart Vanhaesebroeck
- Institute Ludwig Institute for Cancer Research
Tool Details
- Tool name: PI3K-C2a flox
- Tool type: Experimental models
- Tool sub-type: Mouse
- Model: Conditional KO
- Conditional: Yes
- Cell signalling pathway: PI3K/AKT signalling
- Genetic background and cross history: Knock-in mice in which the endogenous PIK3C2B/PI3K-C2beta PI3K gene is flanked by loxp sites.
- Phenotype: Homozygous and heterzygous mice are phenotypically normal.
- Research area: Cancer
- Production details: Knock-in mice in which the endogenous PIK3C2B/PI3K-C2beta PI3K gene is flanked by loxp sites.
- Additional notes: Homozygous and heterzygous mice are phenotypically normal.
- For Research Use Only
References
- • Valet et al. 2015. Blood. 126(9):1128-37. PMID: 26109204.