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Contributor Information

  • Name Bart Vanhaesebroeck
  • Institute Ludwig Institute for Cancer Research ; The University of Edinburgh

Tool Details

  • Tool name: p110beta PI3K-D931A-LacZ
  • Tool type: Experimental models
  • Tool sub-type: Mouse
  • Model: Knock-In
  • Cell signalling pathway: PI3K/AKT signalling
  • Genetic background and cross history: An IRES-lacZ-MC1-neo marker/selection cassette, flanked by loxP sites, was inserted after the STOP codon in the last exon (24) of p110beta PI3K / Knock-in with lacZ casette
  • Phenotype: Have not been characterised in detail as homo- or heterozygous - express lacZ under the control of the p110beta PI3K promotor.
  • Research area: Cancer
  • Production details: An IRES-lacZ-MC1-neo marker/selection cassette, flanked by loxP sites, was inserted after the STOP codon in the last exon (24) of p110beta PI3K / Knock-in with lacZ casette
  • Breeding information: Backcrossed onto C57B6/J for more than 10 generations.
  • Additional notes: Have not been characterised in detail as homo- or heterozygous - express lacZ under the control of the p110beta PI3K promotor.

  • For Research Use Only

Target Details

  • Target: PIK3CB

Application Details

Handling

  • Shipping conditions: Embryo/Spermatoza- Dry Ice

Documentation

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