ANTIBODIES

Contributor Information
- Name Dr. Francisco RuĂz-Cabello Osuna, Dr. Miguel Ăngel LĂłpez-Nevot and Federico Garrido Torres-Puchol, Matias PĂŠrez SĂĄnchez
- Institute Virgen de las Nieves University Hospital, The Andalusian Health Service
- Primary citation Gomez-Morales et al. 1985. Hybridoma. 4(4):369-378. PMID 3864743
Tool Details
- Tool name: Anti-CD9 monoclonal antibody [GR2110]
- Clone: GR2110
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Reactivity: Human
- Host: Mouse
- Cancer type: Blood cancer
- Molecular weight of the target: 24 kDa
- Application: FACS; IHC; ELISA; WB
- Description: CD9 (p24 antigen) is a unique 24 kDa transmembrane polypeptide related to the tetraspanin family. The structure of CD9 is composed of 4 transmembrane domains, with intracellular N- and C-termini. First discovered in a lymphoblastic cell line of the pre-B phenotype, CD9 was later found on platelets and their a-granules, monocytes, B-prelymphocytes, eosinophils, basophils and activated T-lymphocytes. The CD9 molecule associates with other surface proteins such as a6/b4 integrin (CD49f/CD104 molecule) and HLA-DR, suggesting a role in cell adhesion, signal transduction and motility.GR21D10 is a mouse monoclonal antibody of the IgG1 isotype.
- Immunogen: B-ALL cells
- Isotype: IgG1
- Research area: Cancer
- For Research Use Only
References
- • Gomez-Morales et al. 1985. Hybridoma. 4(4):369-378. PMID 3864743