ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-IgM [BC]
- Alternate names: IgM, IgM heavy chain constant region antibody, Immunoglobulin mu antibody, Constant region of heavy chain of IgM antibody, Immunoglobin heavy chain mu constant region antibody
- Clone: BC
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Salmon ; Rainbow Trout
- Host: Mouse
- Application: ELISA ; FACS ; IHC ; IP ; WB
- Strain: Balb/c
- Description: Monoclonal antibody used to monitor vaccine performance in fish. Background and Research Application IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood stock health testing. This anti-IgM antibody provides a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines.
- Immunogen: Ammonium sulphate precipitated rainbow trout Ig fraction
- Isotype: IgG1 kappa
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: Immunoglobulin Heavy Constant Mu (IgM)
- Target background: Monoclonal antibody used to monitor vaccine performance in fish. Background and Research Application IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. Detection of specific antibodies in the serum of animals is an indicator of previous exposure to pathogens which is very valuable for brood stock health testing. This anti-IgM antibody provides a useful tool to monitor vaccine performance in fish and will assist in the development of future vaccines.
Application Details
- Application: ELISA ; FACS ; IHC ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Ichai et al. 2019. Curr Infect Dis Rep. 21(7):25. PMID: 31165271.
- • V??squez et al. 2015. PLoS One. 10(10):e0139718. PMID: 26439739.