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Contributor Information

  • Name Dr. Francisco RuĂ­z-Cabello Osuna,Dr. Miguel Ángel LĂłpez-Nevot and Federico Garrido Torres-Puchol, Susana Pedrinaci Rodriguez
  • Institute Virgen de las Nieves University Hospital, The Andalusian Health Service
  • Primary citation ISBN 0-19-261867-9

Tool Details

  • Tool name: Anti-CD14 monoclonal antibody [GRS1]
  • Clone: GRS1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Blood cancer
  • Molecular weight of the target: 53-55 kDa
  • Application: FACS; IHC; ELISA; WB
  • Description: The CD14 antigen is a glycosylphosphatidylinositol-linked single-chain surface membrane glycoprotein with a molecular weight of 53-55 kDa. It functions as a high-affinity receptor for the lipopolysaccharide (LPS) and LPS-binding protein (LBP) complex. It is found on cells of the myelomonocytic lineage. CD14 antigen is highly expressed on monocytes and macrophages, and weakly expressed on neutrophils. It is also weakly expressed on B-lymphocytes, but absent on T- and NK-lymphocytes, erythrocytes and platelets. It is found on Langerhans cells, follicular dendritic cells and histiocytes. GRS1 is a mouse monoclonal antibody of the IgG1 isotype.
  • Immunogen: U937 cell line
  • Isotype: IgG1
  • Research area: Cancer

  • For Research Use Only

Target Details

  • Target: CD14
  • Target molecular weight: 53-55 kDa

Application Details

  • Application: FACS; IHC; ELISA; WB

Handling

  • Storage buffer: PBS with 0.02% azide
  • Storage conditions:  -15°C to -25°C
  • Shipping conditions: 4°C

Documentation

References

  •   ISBN 0-19-261867-9