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Contributor Information

  • Name Roy Bicknell
  • Institute University of Oxford

Tool Details

  • Tool name: Anti-ACTR2 [149/1]
  • Clone: 149/1
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth.
  • Immunogen: Recombinant fusion protein composed of the intracellular kinase domain of the human type 2 activin receptor fused to gluthathion S-transferase
  • Isotype: IgG1 kappa
  • Research area: Tissue-specific biology; Cell signaling and signal transduction; Cell biology; Developmental biology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Activin receptor type 2 (ACTR2)
  • Target background: ACTR2 is a serine/threonine kinase receptor. Activin signal transduction pathways are implicated in diverse developmental and physiological processes. Activin is implicated in control of vascular endothelial growth.

Application Details

  • Application: IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Storage buffer: DMEM + 5% FCS. Thaw into DMEM + 10% FCS and 10% Iscoves and reduce to DMEM + 5% FCS
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   McCarthy SA et al. 1994. Hybridoma. 13(3):199-203. PMID: 7927363 McCarthy SA et al. 1994. J. Biol. Chem. 269(6):3909-12. PMID: 8307945 Zhu et al. 2007. J Neurosci. 27(50):13770-80. PMID: 18077689.