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Contributor Information

  • Name Helmout Modjtahedi
  • Institute Kingston University
  • Primary citation Arias-Pinilla et al. 2018. Oncotarget. 9(28): 19994–20007. PMID: 29731998

Tool Details

  • Tool name: Anti-CD109 monoclonal antibody [KU43.13A]
  • Clone: KU43.13A
  • Tool type: Antibodies
  • Tool sub-type: Primary antibodies
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Pancreatic cancer
  • Disease: Cancer
  • Molecular weight of the target: 170 KDa
  • Application: IHC, IF, IP, WB, ELISA, FACS
  • Description: KU43.13A mAb detects CD109 antigen with high level of expression in some of the human pancreatic cell lines (e.g. BxPC-3, PANC-1, FA-6 and MIA PaCa-2)
  • Immunogen: BxPC-3 cells
  • Isotype: IgG2a
  • Research area: Cancer

  • For Research Use Only

Target Details

  • Target: CD109
  • Target molecular weight: 170 KDa
  • Target background: CD109 is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. It is highly expressed in cancers of various organs including the pancreas, lung, esophagus, uterine cervix, penis, and gallbladder, but hardly detectable in their normal tissues.

Application Details

  • Application: IHC, IF, IP, WB, ELISA, FACS

Handling

Documentation

References

  •   Arias-Pinilla et al. 2018. Oncotarget. 9(28): 19994–20007. PMID: 29731998
  •   Arias-Pinilla et al. 2020. Sci Rep. 10(1):537. PMID: 31953437