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Contributor Information

  • Institute University of Cambridge

Tool Details

  • Tool name: Anti-Plasminogen [SBF1 C1.21]
  • Clone: SBF1 C1.21
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target:
  • Application: ELISA
  • Strain:
  • Description: Plasminogen is converted to the active serine protease plasmin by proteolytic cleavage by urokinase-type (uPA) and tissue-type (tPA) plasminogen activators. Plasmin is a key enzyme in the fibrinolytic pathway (lysis of the unwanted blood clots). Plasminogen related growth factors are potent effectors of growth, movement and differentiation of epithlia and endothelia. The receptor tyrosine kinsase for HGF/SF is the product of the proto-oncogene c-met.
  • Immunogen: Human Plasminogen
  • Isotype: IgG1
  • Research area: Cancer; Tissue-specific biology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: Plasminogen
  • Target molecular weight:
  • Target background: Plasminogen is converted to the active serine protease plasmin by proteolytic cleavage by urokinase-type (uPA) and tissue-type (tPA) plasminogen activators. Plasmin is a key enzyme in the fibrinolytic pathway (lysis of the unwanted blood clots). Plasminogen related growth factors are potent effectors of growth, movement and differentiation of epithlia and endothelia. The receptor tyrosine kinsase for HGF/SF is the product of the proto-oncogene c-met.

Application Details

  • Application: ELISA

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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