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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-DAF [67]
  • Alternate names: CD55
  • Clone: 67
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; WB
  • Description: Decay Accelerating Factor is a distinctive marker of synovium. Decay Accelerating Factor protects tissues from attack by autologous complement by interfering with the assembly of C3 convertase.
  • Immunogen: Fibronectin purified human monocytes .
  • Isotype: IgG1
  • Research area: Cell biology; Immunology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Decay accelerating factor (DAF, CD55)
  • Target background: Decay Accelerating Factor is a distinctive marker of synovium. Decay Accelerating Factor protects tissues from attack by autologous complement by interfering with the assembly of C3 convertase.

Application Details

  • Application: FACS ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Gheorghe et al. 2011. PLoS One. 6(1):e16378. PMID: 21298002.
  • •  Prostaglandin E2 synthesizing enzymes in rheumatoid arthritis B cells and the effects of B cell depleting therapy on enzyme expression.
  • •  Kamada et al. 2009. Pathol Int. 59(6):382-9. PMID: 19490468.
  • •  Leitinger et al. 2002. J Cell Sci. 115(Pt 5):963-72. PMID: 11870215.
  • •  The involvement of lipid rafts in the regulation of integrin function.
  • •  Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218.
  • •  Features of synovial membrane identified with monoclonal antibodies.