ANTIBODIES

Contributor Information
- Institute Absolute Antibody; The Francis Crick Institute
Tool Details
- Tool name: Anti-Rad51B [1h3/13]
- Clone: 1h3/13
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Recombinant
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Description: RAD51B is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51B is also a component for the homologous recombination pathway.
- Immunogen: Rad51b 1h3/13 was raised against His-tagged human Rad51B, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-PAGE.
- Isotype: IgG2a
- Research area: Genetics
- For Research Use Only
Target Details
- Target: Rad51B
- Target background: RAD51B is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51B is also a component for the homologous recombination pathway.
Application Details
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4ðC
References
- • 11751635
- • 11751635
- • 23149936
- • 23149936
- • 9441753
- • 9441753