ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-MMP2 [4D3]
- Clone: 4D3
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; IF ; IP ; WB
- Strain: Balb/c
- Description: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
- Immunogen: Ovalbumin-conjugated synthetic peptide; TSLGLPPDVQRVD
- Isotype: IgG1
- Research area: Cell biology; Cancer; Tissue-specific biology; Genetics; Metabolism
- Myeloma used: P3X63Ag8.653
- For Research Use Only
Target Details
- Target: Human matrix metalloproteinase 2 (MMP-2)
- Target background: MMP2 degrades type IV collagen and plays an important role in menstrual break down, regulation of vascularization, angiogenesis, and inflammatory response. Mutations of MMP2 are associated with Torg-Winchester syndrome.
Application Details
- Application: ELISA ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -80ðC
- Shipping conditions: Shipping at 4ðC
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References
- • Jeffery et al. 2009. Histopathology. 54(7):820-8. PMID: 19635101.
- • The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers.
- • Lyall et al. 2006. Clin Cancer Res. 12(4):1184-91. PMID: 16489072.
- • Profiling markers of prognosis in colorectal cancer.
- • Curran et al. 2004. Clin Cancer Res. 10(24):8229-34. PMID: 15623598.
- • Matrix metalloproteinase/tissue inhibitors of matrix metalloproteinase phenotype identifies poor prognosis colorectal cancers.
- • Murray et al. 1998. Gut. 43(6):791-7. PMID: 9824606.
- • Matrix metalloproteinases and their inhibitors in gastric cancer.
- • Murray et al. 1998. J Pathol. 185(3):256-61. PMID: 9771478.
- • Matrix metalloproteinase-1 is associated with poor prognosis in oesophageal cancer.