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Contributor Information

  • Name Arnoud Sonnenberg
  • Institute Netherlands Cancer Institute

Tool Details

  • Tool name: Anti-Cytokeratin 10 [DEK10]
  • Alternate names: KRT1; Keratin 1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Dog ; Human ; Feline
  • Host: Mouse
  • Molecular weight of the target: 59 kDa
  • Application: FACS ; WB
  • Strain: Balb/c
  • Description: Cytokeratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are hetero-polymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis
  • Immunogen: Cytoskeletal preperation extracted from humen epidermis
  • Isotype: IgG1
  • Research area: Cancer; Cell biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Cytokeratin 10
  • Target molecular weight: 59 kDa
  • Target background: Cytokeratin-10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are hetero-polymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis

Application Details

  • Application: FACS ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   van der Velden et al. 1993. Head Neck. 15(2):133-46. PMID: 7680025.
  •   Ivanyi et al. 1989. J Pathol. 159(1):7-12. PMID: 2478685.