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Contributor Information

  • Institute Queen Mary University of London

Tool Details

  • Tool name: Anti-AF10 [HAF10 9A5/2]
  • Clone: HAF10 9A5/2
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Application: WB ; ELISA ; FACS ; IHC ; IP ; WB
  • Strain: Balb/c
  • Description: AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein. Clones HAF10 3A6/2, HAF10 3H10/3 and HAF10 9C6/2 are also available.
  • Isotype: IgG2b
  • Research area: Cancer; Genetics
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: AF10
  • Target background: AF10 is a putative transcription factor containing a leucine zipper motif. A t(10;11)(p12;q23) chromosomal translocation present in a proportion of acute myeloid leukaemias results in the expression of an AF10 (carboxy-terminus)-MLL (amino-terminus) fusion protein.

Application Details

  • Application: WB ; ELISA ; FACS ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  AF10 plays a key role in the survival of uncommitted hematopoietic cells.
  • •  Chamorro-Garcia et al. 2012. PLoS One. 7(12):e51626. PMID: 23284727.