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Contributor Information

  • Institute University College London (UCL)

Tool Details

  • Tool name: Anti-AnnexinI [ANEX 5E4/1]
  • Clone: ANEX 5E4/1
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 32 kDa
  • Application: ELISA ; IHC ; IF ; IP ; WB
  • Strain: Balb/c
  • Description: Annexin I has been implicated in the regulation of phagocytosis, cell signaling and cell proliferation.
  • Immunogen: Mixture of native membrane proteins from human bone tissues which would include whole native annexin proteins.
  • Isotype: IgG1
  • Research area: Cell biology; Apoptosis and autophagy; Tissue-specific biology; Cell biology; Cell signaling and signal transduction; Immunology; Biochemistry
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Annexin I
  • Target molecular weight: 32 kDa
  • Target background: Annexin I has been implicated in the regulation of phagocytosis, cell signaling and cell proliferation.

Application Details

  • Application: ELISA ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Dysregulation of anti-inflammatory annexin A1 expression in progressive Crohns Disease.
  • •  Sena et al. 2013. PLoS One. 8(10):e76969. PMID: 24130820.
  • •  Dakin et al. 2012. PLoS One. 7(2):e32333. PMID: 22384219.
  • •  Xiao et al. 2012. Mol Cell Proteomics. 11(2):M111.012112. PMID: 22096114.
  • •  Macrophage sub-populations and the lipoxin A4 receptor implicate active inflammation during equine tendon repair.
  • •  Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry.
  • •  Cao et al. 2008. Mol Cell Proteomics. 7(9):1651-67. PMID: 18504258.
  • •  Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis.
  • •  Herbert et al. 2007. J Biol Chem. 282(47):34468-78. PMID: 17873281.
  • •  The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation.