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Contributor Information

  • Name Itzhak Fischer
  • Institute Drexel University

Tool Details

  • Tool name: Anti-MAP1B antibodies
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Rat
  • Host: Rabbit
  • Application: IHC ; IP ; WB
  • Description: Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized exclusively to growing axons. The levels of MAP1B are mostly down regulated in the adult Central Nervous System, but remain high in neurons and axons of the Peripheral Nervous System and may be important for nerve regeneration.
  • Immunogen: Two polyclonal antibodies were made one with a GST-fusion protein containing the C-terminal amino acid 1836 2076 and the other a GST-fusion protein containing the middle amino acid 11091360 regions of MAP1B
  • Research area: Developmental biology; Neurobiology

  • For Research Use Only

Target Details

  • Target: Both polyclonal antibodies recognise all isoforms of MAP1b
  • Target background: Microtubule-associated protein 1B (MAP1B) is expressed at high levels during development of the nervous system and is localized exclusively to growing axons. The levels of MAP1B are mostly down regulated in the adult Central Nervous System, but remain high in neurons and axons of the Peripheral Nervous System and may be important for nerve regeneration.

Application Details

  • Application: IHC ; IP ; WB

Handling

  • Format: Liquid
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Ma et al. 2000. J Neurosci. 20(6):2112-20. PMID: 10704485.
  • •  Axonal transport of microtubule-associated protein 1B (MAP1B) in the sciatic nerve of adult rat: distinct transport rates of different isoforms.
  • •  Ma et al. 1999. Brain Res. 823(1-2):141-53. PMID: 10095020.
  • •  Induction of microtubule-associated protein 1B expression in Schwann cells during nerve regeneration.
  • •  Boyne et al. 1995. J Neurosci Res. 40(4):439-50. PMID: 7616605.
  • •  Expression and distribution of phosphorylated MAP1B in growing axons of cultured hippocampal neurons.
  • •  Black et al. 1994. J Neurosci. 14(2):857-70. PMID: 8301365.
  • •  Microtubule-associated protein 1b (MAP1b) is concentrated in the distal region of growing axons.