ANTIBODIES

Contributor Information
- Institute BioServ UK Ltd
Tool Details
- Tool name: Anti-CYP450 Aromatase [H4]
- Alternate names: Aromatase, CYPXIX, Cytochrome P-45AROM, Cytochrome P45 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19
- Clone: H4
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 55 kDa
- Application: IHC ; IF ; WB
- Strain: Balb/c
- Description: CYP450 Aromatase is part of the CYP19A1 family involved in the aromatization of androgens to estrogens, a highly conserved mechanism amongst mammals. Clone H4 recognizes a conserved epitope on the CYP450 aromatase, allowing for detection of aromatase levels using various analysis methods.
- Immunogen: Synthetic peptide corresponding to AAs 376-390 of human aromatase (KALEDDVIGYPVKK)
- Isotype: IgG2a
- Research area: Cell signaling and signal transduction
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: CYP450 Aromatase
- Target molecular weight: 55 kDa
- Target background: CYP450 Aromatase is part of the CYP19A1 family involved in the aromatization of androgens to estrogens, a highly conserved mechanism amongst mammals. Clone H4 recognizes a conserved epitope on the CYP450 aromatase, allowing for detection of aromatase levels using various analysis methods.
Application Details
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Shipping conditions: Shipping at 4ðC
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References
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- • Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse graafian follicles.
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- • Steroid receptor and aromatase expression in baboon endometriotic lesions.
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- • Development and validation of a new monoclonal antibody to mammalian aromatase.