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Contributor Information

  • Name Geoff Toms
  • Institute Newcastle University

Tool Details

  • Tool name: Anti-RSV G Glycoprotein [133]
  • Clone: 133
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Virus
  • Host: Mouse
  • Application: IF ; ELISA ; IHC; IF ; WB
  • Description: Identification and location of expression of the G glycoprotein of HRSV of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.
  • Immunogen: Human RSV strain A2 infected HeLa cells
  • Isotype: IgG1
  • Research area: Microbiology
  • Myeloma used: P3/NS1/1-Ag4.1

  • For Research Use Only

Target Details

  • Target: Respiratory syncytial virus subgroup A G glycoprotein
  • Target background: Identification and location of expression of the G glycoprotein of HRSV of both sub-groups A and B . This antibody confers passive protection against HRSV of both subgroups in an animal model of hRSV infection.

Application Details

  • Application: IF ; ELISA ; IHC; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: RPMI + 10% FCS + Hepes (25mM) + glutamine (2mM)
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Vanover et al. 2017. Nat Commun. 8(1):667. PMID: 28939853.
  • •  Shi et al. 2016. Sci Rep. 6:35851. PMID: 27767097.
  • •  Robinson et al. 2014. J Med Virol. 86(7):1267-77. PMID: 24415460.
  • •  Generation and epitope mapping of a sub-group cross-reactive anti-respiratory syncytial virus G glycoprotein monoclonal antibody which is protective in vivo.