ANTIBODIES
Contributor Information
- Institute A*STAR Accelerate Technologies Pte Ltd
Tool Details
- Tool name: Anti-Lamin B receptor [BB3SS4B5]
- Alternate names: DHCR 14B antibody, DHCR14B antibody, Integral nuclear envelope inner membrane protein antibody, Lamin-B receptor antibody, LBR antibody, LBR_HUMAN antibody, LMN 2R antibody, LMN2R antibody, MGC941 antibody, PHA antibody, PRO65 antibody
- Clone: BB3SS4B5
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human ; Mouse
- Host: Mouse
- Application: IHC ; IF ; WB
- Strain: C57BL/6
- Description: Lamin B Receptor (LBR) is a polytopic inner nuclear membrane protein. Its nucleoplasmic domain interacts with components of the nuclear lamina as well as with chromatin, via HP1. LBR also exhibits C14 sterol reductase activity. Deficiency of LBR in humans results in Pelget-Hu??t anomaly featuring hypolobulated granulocyte nuclei. Homozygous loss of LBR causes Greenberg skeletal dysplasia a fetal lethal disorder associated with defective cholesterol metabolism.
- Immunogen: GST fused to N-terminal fragment of human LBR (amino acids residues 1-211)
- Isotype: IgG1 kappa
- Research area: Cell signaling and signal transduction
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Lamin B receptor
- Target background: Lamin B Receptor (LBR) is a polytopic inner nuclear membrane protein. Its nucleoplasmic domain interacts with components of the nuclear lamina as well as with chromatin, via HP1. LBR also exhibits C14 sterol reductase activity. Deficiency of LBR in humans results in Pelget-Hu??t anomaly featuring hypolobulated granulocyte nuclei. Homozygous loss of LBR causes Greenberg skeletal dysplasia a fetal lethal disorder associated with defective cholesterol metabolism.
Application Details
- Application: IHC ; IF ; WB
Handling
- Format: Liquid
- Storage buffer:
- Storage conditions:
- Shipping conditions: Shipping at 4Ă°C
Documentation
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