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Contributor Information

  • Name Lionel Crawford
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-SV40T [PAb419]
  • Clone: PAb419
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Virus
  • Host: Mouse
  • Molecular weight of the target: 94 kDa
  • Application: WB ; IF ; IP
  • Description: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.
  • Immunogen: SV40 large and small T-antigen
  • Isotype: IgG2a
  • Research area: Microbiology

  • For Research Use Only

Target Details

  • Target: N-terminal domain of SV40 large and small T-antigen
  • Target molecular weight: 94 kDa
  • Target background: SV40 is a simian oncogenic polyoma virus. The SV40 large T antigen is an early protein that interacts with the p53 and Rb tumour suppressor proteins.

Application Details

  • Application: WB ; IF ; IP

Handling

  • Format: Liquid
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Goolsby et al. 1991. Cytometry. 12(8):748-56. PMID: 1665408.
  • •  Viral and cellular oncogene expression during progressive malignant transformation of SV40 transformed human fibroblasts.
  • •  Monoclonal antibodies specific for simian virus 40 tumor antigens.
  • •  Harlow et al. 1981. J Virol. 39(3):861-9. PMID: 6169844.