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Contributor Information

  • Name Stephen West
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-RuvB [SWE4]
  • Clone: SWE4
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: E.coli
  • Host: Rabbit
  • Application: IP ; WB
  • Description: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions.
  • Immunogen: RuvB (E-coli) purified protein
  • Research area: Genetics

  • For Research Use Only

Target Details

  • Target: RuvB
  • Target background: During genetic recombination and post replication repair of DNA damage, RuvA and RuvB (a helicase) act in a complex to promote branch migration of Holliday junctions.

Application Details

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: Serum
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Davies et al. 1998. Curr Biol. 8(12):725-7. PMID: 9637927.
  • •  Formation of RuvABC-Holliday junction complexes in vitro.
  • •  Eggleston et al. 1997. Cell. 89(4):607-17. PMID: 9160752.
  • •  In vitro reconstitution of the late steps of genetic recombination in E. coli.