Product Image

Contributor Information

  • Name Margaret Goodall
  • Institute University of Birmingham

Tool Details

  • Tool name: Anti-Follicular Dendritic Cells [BU58]
  • Alternate names: DC;APC;antigen presenting cells;
  • Clone: BU58
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC
  • Strain: Balb/c
  • Description: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells.
  • Immunogen: B lymphoblastoid cell line: HFB1
  • Isotype: IgM
  • Research area: Cell biology; Immunology

  • For Research Use Only

Target Details

  • Target: Dendritic cells
  • Target background: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells.

Application Details

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917.