ANTIBODIES

Contributor Information
- Name Margaret Goodall
- Institute University of Birmingham
Tool Details
- Tool name: Anti-Follicular Dendritic Cells [BU58]
- Alternate names: DC;APC;antigen presenting cells;
- Clone: BU58
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Strain: Balb/c
- Description: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells.
- Immunogen: B lymphoblastoid cell line: HFB1
- Isotype: IgM
- Research area: Cell biology; Immunology
- For Research Use Only
Target Details
- Target: Dendritic cells
- Target background: Follicular dendritic cells (FDC), described as embryonal non-phagocytic reticulum cells are found exclusively in B cell-rich follicles of peripheral lymphoid tissue. In the germinal centres of secondary follicles their cytoplasmic processes form a dense network closely associated with the lymphoid cells. Although FDCs have a very dendritic morphology they are not dendritic cells and FDCs are not derived from bone-marrow haematopoietic stem cells.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Johnson et al. 1986. Clin Exp Immunol. 64(1):205-13. PMID: 3524917.