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Contributor Information

  • Institute A*STAR Accelerate Technologies Pte Ltd

Tool Details

  • Tool name: Anti-Claudin 16 [4C10]
  • Alternate names: CLD16
  • Clone: 4C10
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IF
  • Description: Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen.
  • Immunogen: CLD16-KLH peptide conjugate
  • Isotype: IgM
  • Research area: Cell biology
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Claudin-16
  • Target background: Claudin-16 (CLD16) is component of the tight junction in kidney. It is exclusively expressed in the thick ascending of limb of Henle (TALH). This is involved in the parcellular transport of Mg2+ in the TALH. Mutations in claudin-16 have been implicated in the loss of Mg in the urine. Claudin16 antibody is raised using the extracellular loop 1 as an antigen.

Application Details

  • Application: IF

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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