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Contributor Information

  • Name Joyce Taylor-Papadimitriou
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-Interferon [ST126]
  • Clone: ST126
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Molecular weight of the target: 18-25 kDa
  • Application: Fn
  • Strain: Balb/c
  • Description: Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon.
  • Immunogen: Human interferon (HuIFN) produced by Namalwa cells (HuIFN-aN)
  • Isotype: IgG2b
  • Research area: Cancer; Immunology
  • Myeloma used: P3X63Ag8.653

  • For Research Use Only

Target Details

  • Target: Human interferon alpha subspecies
  • Target molecular weight: 18-25 kDa
  • Target background: Distinguishes between sub-species of human interferon alpha and can be used to detect interferon oligomers. Neutralises anti-viral activity of interferon.

Application Details

  • Application: Fn

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Shearer et al. 1992. Int J Oncol. 1(3):303-12. PMID: 21584547.
  • •  Monoclonal-antibodies to huifn-alpha species applied to the study of IFN-receptor interaction indicate that receptor down-regulation does not occur in daudi cells.
  • •  Taylor-Papadimitriou et al. 1987. J Immunol. 139(10):3375-81. PMID: 2445813.
  • •  Epitopes of human interferon-alpha defined by the reaction of monoclonal antibodies with alpha interferons and interferon analogues.
  • •  Shearer et al. 1984. J Immunol. 133(6):3096-101. PMID: 6491281.
  • •  Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers.