ANTIBODIES
Contributor Information
- Name John Kemshead
- Institute Imperial Cancer Research Fund
Tool Details
- Tool name: Anti-Neuroblastoma [FMG25]
- Clone: FMG25
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Cancer type: Neurological cancer
- Application: FACS
- Strain: Balb/c
- Description: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
- Immunogen: Human cutaneous T cell lymphoma (HUT 78), SPF female Balb/c mice were injected i.p with 2 x 10*5 cells in complete Freund's adjuvant. 30 days later a 2nd i.p injection of 2 x 10*5 cells without adjuvant was given. Fusion was 5 days
- Isotype: IgG1
- Research area: Cancer; Cell biology
- Myeloma used: P3X63Ag8
- For Research Use Only
Target Details
- Target: Human Neuroblastoma
- Target background: Useful diagnostic reagent to differentiate between neuroblastoma and rhabdomyosarcoma. May be useful as one of a panel of reagents to detect and remove tumour cells from bone marrow harvested for autologous transplantation. Also cross reacts with normal brain and peripheral nerve. The antibody does not bind to other small round-cell tumours of childhood.
Application Details
- Application: FACS
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Gibson et al. 1987. Int J Cancer. 39(5):554-9. PMID: 3494688.
- • A monoclonal antibody (FMG25) that can differentiate neuroblastoma from other small round-cell tumours of childhood.
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