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Contributor Information

  • Name David Baldwin
  • Institute University of Nottingham

Tool Details

  • Tool name: Anti-Y hapten (C14) [NCRC55]
  • Alternate names: C14
  • Clone: NCRC55
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; RIA
  • Strain: Balb/c
  • Description: Y haptens are carbohydrate surface antigens formed by the difucosylation of Type-2-blood-group chains. The expression of Y haptens is frequently elevated in colo-rectal tumours in comparison to adjacent, apparently normal tissue.
  • Isotype: IgG3
  • Research area: Cancer; Immunology
  • Myeloma used: NS0

  • For Research Use Only

Target Details

  • Target: Y hapten
  • Target background: Y haptens are carbohydrate surface antigens formed by the difucosylation of Type-2-blood-group chains. The expression of Y haptens is frequently elevated in colo-rectal tumours in comparison to adjacent, apparently normal tissue.

Application Details

  • Application: FACS ; RIA

Handling

  • Format: Liquid
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Price et al. 1986. Cancer Lett. 33(1):83-9. PMID: 3768863.
  • •  Association of the Y hapten with glycoproteins, glycolipids and carcinoembryonic antigen in colorectal carcinoma.
  • •  Brown et al. 1983. Biosci Rep. 3(2):163-70. PMID: 6189529.
  • •  A monoclonal antibody against human colonic adenoma recognizes difucosylated Type-2-blood-group chains.