ANTIBODIES
Contributor Information
- Name Fiona Watt
- Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
- Tool name: Anti-Integrin a2 [HAS-6]
- Clone: HAS-6
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Host: Mouse
- Molecular weight of the target:
- Application: FACS ; IHC ; IP
- Description: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
- Immunogen:
- Isotype: IgG2a
- Research area: Cell biology; Cancer; Cell signaling and signal transduction; Metabolism
- Myeloma used: Sp2/0-Ag14
- For Research Use Only
Target Details
- Target: Integrin alpha 2 subunit (CD49b)
- Target molecular weight:
- Target background: Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
Application Details
- Application: FACS ; IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Sugiyama et al. 1993. Carcinogenesis. 14(10):2171-6. PMID: 7693359.
- • Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas.
- • Tenchini et al. 1993. Cell Adhes Commun. 1(1):55-66. PMID: 7521749.
- • Evidence against a major role for integrins in calcium-dependent intercellular adhesion of epidermal keratinocytes.
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