ANTIBODIES

Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-FCGR2 [2ZC115]
- Alternate names: Fc Fragment Of IgG Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2; FCG2; CD32; FCGR2; CD32B
- Clone: 2ZC115
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC
- Description: Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.
- Immunogen: Hairy cell leukaemia cells
- Isotype: IgG2a
- Research area: Immunology; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Fc gamma Recptor II (FCGR2, CD32)
- Target background: Human Fc gamma receptor II (CD32) exists in at least six isoforms originating from three different genes (Fc gamma RII A, B, and C). The CD32 molecule is a low affinity receptor for immune complexed IgG and has signal-transducing capabilities involved with humoral and cell-mediated immune responses. It is expressed by Monocytes, granulocytes, B cells, eosinophils.
Application Details
- Application: IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Greenman J et al. 1991. Mol Immunol 28:1243-54. PMID: 1835758 Pulford K et al. 1986. Immunology 57:71-6. PMID: 3484721