ANTIBODIES

Contributor Information
- Name Ayham Alnabulsi
- Institute Vertebrate Antibodies Limited
Tool Details
- Tool name: Anti-Cytochrome P450 27A1 [V29-P4B8*B2]
- Clone: V29-P4B8*B2
- Tool type: Antibodies
- Tool sub-type: Primary antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB ; ELISA ; IHC ; WB
- Description: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
- Immunogen: Ovalbumin-conjugated synthetic peptide KVVLAPETGEL (C-terminal sequence)
- Isotype: IgG1 kappa
- Research area: Cancer; Tissue-specific biology; Cell signaling and signal transduction; Metabolism
- For Research Use Only
Target Details
- Target: Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1), Sterol 27-Hydroxylase
- Target background: Cytochrome P450 27A1 (CYP27A1) catalyzes the first step in the oxidation of the side chain of sterol intermediates; the 27-hydroxylation of 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol. Has also a vitamin D3-25-hydroxylase activity.
Application Details
- Application: IHC ; WB ; ELISA ; IHC ; WB
Handling
- Format: Liquid
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- • Swan et al. 2016. Oncotarget. :. PMID: 27341022.