ANTIBODIES
Contributor Information
- Name Karen Pulford
- Institute University of Oxford
Tool Details
- Tool name: Anti-Leu2 [X107]
- Alternate names: CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; CD8 Antigen; Alpha Polypeptide (P32); MAL; T-Cell Surface Glycoprotein CD8 Alpha Chain; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2; T8 T-Cell Antigen; CD8a Antigen; Leu2; P32
- Clone: X107
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC
- Description: Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.
- Immunogen: Synthetic peptide ( the 13 c-terminal residues of the cytoplasmic domain of human CD8a)
- Isotype: Not Known
- Research area: Immunology; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Leu2 (CD8)
- Target background: Leu-2 (CD8) is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells which make up 30% of circulating T cells. X107 may be used to detect these cells in tissue sections and also their neoplastic counterparts.
Application Details
- Application: FACS ; IHC
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Storage buffer: RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
Related Tools
References
- • Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press. p 1076. ISBN-13: 978-0192618672
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