ANTIBODIES

Contributor Information
- Name Jacqueline Cordell
- Institute University of Oxford
Tool Details
- Tool name: Anti-Leu1 [CD5/54/F6]
- Alternate names: CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
- Clone: CD5/54/F6
- Tool type: Antibodies
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Bovine ; Chicken ; Horse ; Guinea Pig ; Opossum ; Pig ; Primate ; Rat ; Rabbit
- Host: Mouse
- Cancer type: Blood cancer
- Application: IHC ; WB
- Description: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue
- Immunogen: Peptide from the intracellular region of CD5 (SSMQPDNSSDSDYDLHGAQRL)
- Isotype: IgG1
- Research area: Immunology; Stem cell biology
- Myeloma used: P3/NS1/1-Ag4.1
- For Research Use Only
Target Details
- Target: Leu1 (CD5)
- Target background: CD5 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. CD5 has utility for the monitoring of T-cell numbers in peripheral blood and the identification of leukaemias of T cell origin. Absence of the CD5 marker on childhood ALL cells is associated with a more favourable prognosis. Detects CD5 on mammalian tissue
Application Details
- Application: IHC ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15ðC to -25ðC
- Shipping conditions: Shipping at 4ðC
Related Tools
References
- • Jones et al. 1993. J Immunol. 150(12):5429-35. PMID: 8515069.
- • Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies.