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Contributor Information

  • Institute University of Florida

Tool Details

  • Tool name: Anti-muscleblind-like protein 1 [3A4-1E9]
  • Alternate names: Muscleblind Like Splicing Regulator 1; MBNL1
  • Tool type: Antibodies
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Rat ; Mouse
  • Host: Mouse
  • Application: WB ; IHC ; IF ; IP
  • Description: Muscleblind-like protein 1 (MBNL1) is well characterized in its role in Myotonic dystrophy, atype of muscular dystrophy and long term genetic disorder that effects muscle function. MBLN1 regulates alternative splicing and acts as both an activator and repressor in terminal muscle differentiation. Defects in its repressor activity have been shown to lead to muscular diseases.
  • Immunogen: Recombinant MBNL1 fusion protein of human origin
  • Isotype: IgG1 kappa
  • Research area: Genetics

  • For Research Use Only

Target Details

  • Target: Muscleblind-like protein 1
  • Target background: Muscleblind-like protein 1 (MBNL1) is well characterized in its role in Myotonic dystrophy, atype of muscular dystrophy and long term genetic disorder that effects muscle function. MBLN1 regulates alternative splicing and acts as both an activator and repressor in terminal muscle differentiation. Defects in its repressor activity have been shown to lead to muscular diseases.

Application Details

  • Application: WB ; IHC ; IF ; IP

Handling

  • Format: Liquid
  • Storage buffer:
  • Storage conditions:
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Mankodi et al. 2003. Ann Neurol. 54(6):760-8. PMID: 14681885.