ANTIBODIES
Contributor Information
- Name Deborah Buckle ; John Marshall
- Institute Queen Mary University of London
Tool Details
- Tool name: Anti-ICAM1 [P1W16]
- Alternate names: Intercellular Adhesion Molecule 1; Major Group Rhinovirus Receptor; ICAM-1; Cell Surface Glycoprotein P3.58; Human Rhinovirus Receptor; P3.58; CD54; BB2
- Clone: P1W16
- Tool type: Antibodies
- Class: Monoclonal
- Conjugate: Unconjugated
- Reactivity: Human
- Host: Mouse
- Molecular weight of the target: 85-115
- Application: FACS ; IHC ; IF ; IP
- Strain: Balb/c
- Description: ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma.
- Immunogen: V(+)B2- Human Ocular melanoma line
- Isotype: IgG1 kappa
- Research area: Cell biology; Tissue-specific biology; Immunology; Stem cell biology
- For Research Use Only
Target Details
- Target: ICAM1 (CD54)
- Target molecular weight: 85-115
- Target background: ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-1 is expressed in haemopoietic cells and vascular endothelium. Cytokine activation causes ICAM-1 expression in other cell types such as fibroblasts and keratinocytes. ICAM-1 is involved in leukocyte recruitment and inflammation. ICAM-1 binds LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). P1W16 may be useful for prognosis of malignant melanoma.
Application Details
- Application: FACS ; IHC ; IF ; IP
Handling
- Format: Liquid
- Concentration: 0.9mg/ml
- Storage buffer: DMEM + 5% FCS
- Storage conditions: -15Ă°C to -25Ă°C
- Shipping conditions: Shipping at 4Ă°C
Documentation
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