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Contributor Information

  • Name Nancy Hogg
  • Institute Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details

  • Tool name: Anti-S100a8 [NH9]
  • Alternate names: mMRP-8, calgranulin A
  • Clone: NH9
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Polyclonal
  • Conjugate: Unconjugated
  • Reactivity: Mouse
  • Host: Rabbit
  • Molecular weight of the target: 8 kDa
  • Application: WB
  • Description: Together with heterodimeric partner S100a9, S100a8 is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumour models.
  • Immunogen: Synthesised full length mouse S100a8
  • Research area: Cancer; Cell signaling and signal transduction; Immunology; Neurobiology

  • For Research Use Only

Target Details

  • Target: S100a8
  • Target molecular weight: 8 kDa
  • Target background: Together with heterodimeric partner S100a9, S100a8 is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumour models.

Application Details

  • Application: WB

Handling

  • Format: Liquid
  • Storage buffer: Whole serum
  • Storage conditions: -80°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Baker et al. 2011. Dev Dyn. 240(9):2194-203. PMID: 22016186.
  • •  Distinct roles for S100a8 in early embryo development and in the maternal deciduum.
  • •  Hobbs et al. 2003. Mol Cell Biol. 23(7):2564-76. PMID: 12640137.
  • •  Myeloid cell function in MRP-14 (S100A9) null mice.