Product Image

Contributor Information

  • Institute Yale University

Tool Details

  • Tool name: Anti-Thy 1 [Y19]
  • Tool type: Antibodies
  • Tool sub-type: Primary Antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Description: Monoclonal antibody which can identify stem cell markers and processes within mature neurones. Background and Research Application Thy-1 or CD90 is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Thy-1 is expressed on thymocytes, CD34+ prothymocytes, hematopoietic stem cells, neurons, a small subset of human foetal liver cells, cord blood cells, and bone marrow cells. It is also found on a subset of immature, CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+. Thy-1 is involved in regulation of adhesion and signal transduction by T cells.
  • Immunogen: P04216
  • Immunogen UniProt ID: P04216
  • Research area: Immunology

  • For Research Use Only

Target Details

  • Target: Thy1, CD90
  • Target background: Monoclonal antibody which can identify stem cell markers and processes within mature neurones. Background and Research Application Thy-1 or CD90 is a 2537 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain. Thy-1 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Thy-1 is expressed on thymocytes, CD34+ prothymocytes, hematopoietic stem cells, neurons, a small subset of human foetal liver cells, cord blood cells, and bone marrow cells. It is also found on a subset of immature, CD34+ cells and a distinct subset of mature CD34- cells that are CD3+CD4+. Thy-1 is involved in regulation of adhesion and signal transduction by T cells.

Application Details

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20°C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4°C

Documentation

References

  •   Knapp et al. 2010. PLoS One. 5(7):e11653. PMID: 20657836.
  •   Roth et al. 1997. J Exp Biol. 200(Pt 14):2057-62. PMID: 9246787.
  •   Liu et al. 1990. J Exp Med. 172(6):1735-9. PMID: 2147950.
  •   Jones et al. 1981. Eur J Immunol. 11(7):584-92. PMID: 6974646.