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Contributor Information

  • Name Irene Leigh
  • Institute Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details

  • Tool name: Anti-Keratin6 [LL020]
  • Clone: LL020
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IF ; WB
  • Description: LL020 can be used as a proliferation marker.
  • Immunogen: Carboxy terminal peptide
  • Isotype: IgM
  • Research area: Cell signaling and signal transduction
  • Myeloma used: Sp2/0-Ag14

  • For Research Use Only

Target Details

  • Target: Keratin 6
  • Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin.

Application Details

  • Application: IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

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References

  • •  Hughes et al. 1996. Br J Dermatol. 134(2):247-56. PMID: 8746337.
  • •  Keratin expression in pilosebaceous epithelia in truncal skin of acne patients.
  • •  Markey et al. 1992. Br J Dermatol. 126(2):154-60. PMID: 1371396.
  • •  Keratin expression in basal cell carcinomas.