EXPERIMENTAL MODELS
Contributor Information
- Name Ben Emery
- Institute Oregon Health & Science University
Tool Details
- Tool name: Myrf mouse
- Tool type: Experimental models
- Tool sub-type: Mouse
- Disease: Conditional ablation of Myrf gene on a defined genetic background
- Model: Conditional KO
- Conditional: Yes
- Conditional description: conditional ablation of the Myrf gene
- Genetic background and cross history: backcrossed MyrfFl/Fl mouse line in C57B/6N genetic background
- Phenotype: loxP flanked knock-in allele of Myrf
- Strain: C57BL/6
- Description: loxP flanked Myrf gene, critical for myelination of CNS.
- Research area: Neurobiology
- For Research Use Only
Target Details
- Target: Myrf (myelin regulatory factor)
Application Details
Handling
- Shipping conditions: Embryo/Spermatoza- Dry Ice
Documentation
Related Tools
References
- • Rossetti et al. 2019. Am J Med Genet A. 179(7):1376-1382. PMID: 31069960.
- • Garnai et al. 2019. PLoS Genet. 15(5):e1008130. PMID: 31048900.
- • Emery et al. 2009. Cell. 138(1):172-85. PMID: 19596243.
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