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Contributor Information

  • Name Anne-Marie Mes-Masson and Diane Provencher
  • Institute Centre Hospitalier de L’université de Montréal
  • Primary citation Sauriol A et al. 2020. Cancers. 12(8):2222. PMID: 32784519

Tool Details

  • Tool name: OV-3331 cell line
  • Alternate names: OV-3331
  • Tool type: Cell Lines
  • Organism: Human
  • Donor: Grade 3 – Stage IIIC; Mutations: TP53 Exon 6; Carboplatin/Taxol/CEP0906A2203E1/Doxorubicin
  • Tissue: Derived from ascites of patient diagnosed with adenocarcinoma at specific time points at diagnosis and relapse
  • Gender: Female
  • Cancer type: Gynaecologic cancer
  • Morphology: Formed loose aggregates rather than solid spheroids
  • Growth properties: Adherent
  • CRISPR: No
  • Receptors of note: No
  • Description: Epithelial ovarian cancer cell lines spontaneously derived from ascites of patient diagnosed with adenocarcinoma
  • Research area: Cancer
  • Production details: Established from the cellular fraction of ascites collected by centrifugation. The cell lines were then maintained for 40 days in OSE with medium replaced weekly.
  • Additional notes: Patient 3331 did not undergo cytoreductive sugery. Patient was age 72 at diagnosis and no prior history of cancer. Treatment involved Carboplatin, Paclitaxel, and Epothilone B. Year of sampling was 2007

  • For Research Use Only

Target Details

Application Details

Handling

  • Growth medium: OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin
  • Temperature: 37C
  • Atmosphere: Low oxygen conditions of 7% O2 and 5% CO2
  • Cultured in antibiotics?: Amphotericin B and Gentamicin

Documentation

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References

  • •  Gaia-Oltean et al. 2021. Exp Ther Med. 21(3):243. PMID: 33603851 Canals Hernaez et al. 2020. J Immunother Cancer. 8(2):e001128. PMID: 33243933 Borzdzi?owska et al. 2022. Biomedicines. 11
  • •  10(5):1116. PMID: 35625852 Meng et al. 2023. J Anim Sci. 3
  • •  101:skad215. PMID: 37351870 Koni et al. 2020. Int J Mol Sci. 18
  • •  21(20):7697. PMID: 33080952