ANTIBODIES
Contributor Information
- Name Sabine Costagliola
- Institute Universite Libre de Bruxelles
- Primary citation Costagliola et al. 2000. J Clin Endocrinol Metab. 85(7):2366-9. PMID: 10902780.
Tool Details
- Tool name: Anti- sodium/iodide symporter (NIS) [VJ1]
- Clone: VJ1
- Tool type: Antibody
- Tool sub-type: Primary Antibody
- Class: Monoclonal
- Reactivity: Human
- Host: Mice
- Cancer type: Thyroid cancer
- Application: FACS, IF, IHC, not WB after epitope denaturation
- Description: VJ1 is a monoclonal antibody to human NIS that recognizes an epitope located between amino acid 272 and 515 located within the last three extracellular loops
- Immunogen: pCDNA3-hNIS (genetic immunization)
- Isotype: IgG1,k
- Research area: Cancer
- For Research Use Only
Target Details
- Target: Human Sodium iodide symporter (NIS), epitope between amino acid 272 and 515 located within the last three extracellular loops
- Target background: Sodium iodide symporter (NIS) is a gene responsible for the transport of iodide into the thyroid gland and is located in the basolateral membrane of thyroid follicular cells. NIS is also expressed in extrathyroidal tissues, including transformed cells, and its expression may be used as a biomarker for diagnostic, prognostic, and therapeutic purposes.
Application Details
- Application: FACS, IF, IHC, not WB after epitope denaturation
Handling
Documentation
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