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Contributor Information

  • Name Isabelle Baconguis & Arpita Bharadwaj
  • Institute Oregon Health & Science University
  • Primary citation Noreng et al. 2018. Elife 7:e39340. PMID: 30251954

Tool Details

  • Tool name: Anti-Epithelial sodium channel (ENaC) beta subunit [10D4] monoclonal antibody
  • Alternate names: AB_2744525
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Reactivity: Human
  • Host: Mouse
  • Cancer type: Genitourinary cancer
  • Molecular weight of the target: 150 kDa
  • Application: IHC, DB
  • Description: ENaC is a channel found on the surface of epithelial cells and controls the volume of the fluid surrounding cells, blood pressure and the volume of liquid in the airways. The 7B1 and 10D4 mAbs were selected because they recognize tertiary epitopes of ENaC
  • Immunogen: Recombinant human ENaC
  • Isotype: IgG1
  • Research area: Cell signaling and signal transduction

  • For Research Use Only

Target Details

  • Target: Sodium channel, beta subunit
  • Target molecular weight: 150 kDa

Application Details

  • Application: IHC, DB

Handling

  • Storage buffer: OptiMEM, 7% Ultralow IgG FBS, 0.5% v/v Hybridoma Cloning Factor, Antibiotic-antimycotic solution
  • Storage conditions: Store at 4°C short term, store at -20°C long term
  • Shipping conditions: Shipment at 4°C

Documentation

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References

  • •  Noreng et al. 2018. Elife 7:e39340. PMID: 30251954