Product Image

Contributor Information

  • Name Jose Villadangos ; Hamish McWilliam
  • Institute University of Melbourne

Tool Details

  • Tool name: Anti-MR1 [8G3]
  • Alternate names: Major histocompatability complex class I-related gene protein
  • Tool type: Antibodies
  • Tool sub-type: Primary antibody
  • Class: Monoclonal
  • Conjugate: Unconjugated
  • Reactivity: Human ; Mouse
  • Host: Mouse
  • Molecular weight of the target: 42 kDa
  • Application: IP ; WB
  • Strain: C57BL/6
  • Description: MR1 presents small metabolite antigens from diverse microbes to activate an abundant T cell population called mucosal associated invariant T cells (MAIT cells). In this way MR1 activates MAIT cells which results in anti-microbial immunity and tissue repair.
  • Immunogen: Peptide sequence from MR1: pwmaenlapdhwer
  • Immunogen UniProt ID: Q95460
  • Isotype: IgG2a kappa
  • Research area: Immunology; Cancer
  • Myeloma used: Sp2/0

  • For Research Use Only

Target Details

  • Target: MR1
  • Target molecular weight: 42 kDa
  • Target background: MR1 presents small metabolite antigens from diverse microbes to activate an abundant T cell population called mucosal associated invariant T cells (MAIT cells). In this way MR1 activates MAIT cells which results in anti-microbial immunity and tissue repair.

Application Details

  • Application: IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15°C to -25°C
  • Shipping conditions: Shipping at 4°C

Documentation

Related Tools

Product Image

Anti-HA Tag [16.43] mAb

#151835
Product Image

Anti-CD3 e [NKIT3a]

#154754
Product Image

Anti-MCM5 [A4.6G8.A4.F10]

#151422

References

  • •  McWilliam et al. 2020. Proc Natl Acad Sci U S A. 117(40):24974-24985. PMID: 32958637.